Robert Krikorian and colleagues point out that previous studies in laboratory animals suggest that eating blueberries may help boost memory in the aged. Until now, however, there had been little scientific work aimed at testing the effect of blueberry supplementation on memory in people.

In the study, one group of volunteers in their 70s with early memory decline drank the equivalent of 2-2 l/2 cups of a commercially available blueberry juice every day for two months. A control group drank a beverage without blueberry juice. The blueberry juice group showed significant improvement on learning and memory tests, the scientists say. “These preliminary memory findings are encouraging and suggest that consistent supplementation with blueberries may offer an approach to forestall or mitigate neurodegeneration,” said the report. The research involved scientists from the University of Cincinnati, the U.S. Department of Agriculture, and the Canadian department of agriculture.

ARTICLE FOR IMMEDIATE RELEASE: “Blueberry Supplementation Improves Memory in Older Adults”

DOWNLOAD FULL TEXT ARTICLE http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/jf9029332

Source: Michael Bernstein
American Chemical Society

Researchers from the newly founded Max Planck Institute for Biology of Ageing in Cologne have studied whether health benefit stem from a reduction in specific nutrients or calorie intake in general by manipulating the diet of female fruit flies. The fruit flies were fed a diet of yeast, sugar and water, but with differing amounts of key nutrients, such as vitamins, lipids and amino acids. The scientists were able to show that longevity and fertility are affected by a combination of the type and amount of amino acids; whilst varying the amount of the other nutrients had little or no effect. Furthermore, the researchers found out in previous studies that levels of a particular amino acid – methionine – were crucial to increasing lifespan without decreasing fertility. By carefully manipulating the balance of amino acids, both lifespan and fertility were maximised. For the first time, this indicates that it is possible to extend lifespan without wholesale dietary restriction and without lowering reproductive capacity.

As the effects of dietary restriction on lifespan is evolutionary conserved – observed in different organisms – researchers believe that the essential mechanisms apply to it as well. Even though the human genome has about four times the number of genes as the fruit fly genome, there are many similarities on a genetic level, allowing these results to be of significance for humans as well.

Original work:
Richard C. Grandison, Matthew D. W. Piper & Linda Partridge
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
Nature, December 3, 2009, doi:10.1038/nature08619

Source: Katharina Möller
Max-Planck-Gesellschaft