Obesity Gene May Be Associated With Dementia

A gene linked to obesity may also be associated with dementia according to research published in the Proceedings of the National Academy of Sciences.

Researchers at the University of California, Los Angeles generated 3D maps of over 200 healthy elderly people’s brains and found a pattern of diminished brain volume in people with specific DNA sequence within the fat mass and obesity-associated (FTO) gene.

‘We’ve known for some time that there’s a link between obesity in mid life and the development of Alzheimer’s disease. However this study suggests that healthy people who carry a specific DNA sequence associated with obesity could be at a greater risk of developing dementia. A reduction in people’s brain tissue was observed but this wasn’t linked to other obesity-related factors such as cholesterol levels, diabetes or high blood pressure. Read more